Therapeutic Potential of Janus-activated Kinase-2 Inhibitors for the Management of Myelofibrosis
نویسندگان
چکیده
منابع مشابه
Therapeutic potential of Janus-activated kinase-2 inhibitors for the management of myelofibrosis.
Myelofibrosis (either primary or postpolycythemia vera/essential thrombocythemia) is a chronic and debilitating myeloproliferative neoplasm for which there is no well-accepted standard of care. Clinical manifestations of this disease (e.g., cytopenias, splenomegaly, bone marrow fibrosis) and constitutional symptoms (e.g., hypercatabolic state, fatigue, night sweats, fever) create significant tr...
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Splenomegaly is a common sign of primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (post-PV MF), and post-essential thrombocythemia myelofibrosis (post-ET MF) that is associated with bothersome symptoms, which have a significant negative impact on patients' quality of life. It may also be present in patients with advanced polycythemia vera (PV) or essential thrombocythemia (ET)....
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چکیده ندارد.
15 صفحه اولManaging Patients With Myelofibrosis in the Era of Janus Kinase Inhibitors
Myelofibrosis (MF) is a rare, chronic myeloproliferative neoplasm. Oncology advanced practitioners (APs), including nurse practitioners, oncology nurses, pharmacists, and physician assistants, who are caring for patients with MF play important roles in patient education and the management of patient expectations. Vigilance in the monitoring of disease progression, treatment response, and advers...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2010
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-09-2836